Single Particle Analyses Toolbox: The Key to Unlocking the Heterogeneity of Extracellular Vesicles
Randy Carney,
Assistant Professor,
University of California-Davis
The heterogeneity in composition and structure of individual EVs strongly contributes to their varied functions with respect to therapeutics. Yet it remains a challenge to examine structure-function at the resolution of single vesicles. In this talk, I will introduce a suite of high throughput commercial and custom tools that probe the structure and composition of single EVs, with a focus on spectroscopic techniques. I will examine best practices and key advantages of each technique, and provide an outlook of what is needed still to advance their study.
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