PKU-SMART-Sensor: An Integrated Point-of-Care System for the Self-Testing of Phenylalanine in Biological Specimen
Salvatore Petralia,
Assistant professor,
University of catania
PKU-SMART-Sensor is an an integrated Point-of-Care system composed by a
miniaturized and low-cost biosensor, a reader for thermal processes and
optical reading, wirelessly connected with a smartphone for the remote
control and data acquisition. The biosensor integrates all the processes
required for the Phe monitoring as: [1] sample treatments, [2]
enzymatic recognition based on Phenylalaninedehydrogenase/NAD+-dependent
and [3] colorimetric-transduction process based on the in-situ
formation of plasmonic gold nanostructures.
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