Acceleration of Drug Discovery Through the Judicious Application of Enabling Chemistry Technology
Stevan Djuric,
Vice President, Discovery Chemistry & Technology and Distinguished Research Fellow,
AbbVie
The talk will focus on efforts to speed up components of the Drug
discovery process that can be influenced by chemistry, namely, cycle
time, probability of success and cost of goods.
The following will be highlighted:
- Flow chemistry platforms for compound library production
- Fully integrated synthesis-purification- bioassay platforms
- Flow chemistry at high temperature to access key heterocyclic compounds for FBDD activities
- Reaction acceleration using microdroplet chemistry
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