IBS Symposium Talks Agenda

Symposium Registration

Opening Remarks: Convener and President of the IBS

G.N. Ramachandran Memorial Lecture Chairperson: Raghavan Varadarajan

High-resolution 3D Electron Microscopy: Progress and New Opportunities
Sriram Subramaniam, Senior Investigator, National Institute Of Health, United States of America

Group Photo and Tea

Session 1 Chairperson: G. Krishnamoorthy

Dipole Potential: A Novel Approach to Explore Membrane Organization and Function
Amitabha Chattopadhyay, Outstanding Scientist (Director Level), Centre for Cellular & Molecular Biology, India

Atomic Force Spectroscopy Approach to MDR-TB Detection
Rupa Mukhopadhyay, Associate Professor, Indian Association for the Cultivation of Science, India

Computational Studies to Understand Mechanism of Action of Prolyloligopeptidases
Ramanathan Sowdhamini, Professor, National Centre for Biological Sciences, India

Structures-Toxicity Link of Protein Aggregates in Parkinson’s Disease
Ashutosh Kumar, Assistant Professor, Indian Institute of Technology Bombay, India

Protein Structure and Dynamics Specific to cis-Proline
Gautam Basu, Professor, Bose Institute, India

Lunch and Executive Committee Meeting

Poster Evaluation and Tea

Session 2 Chairperson: Sriram Subramaniam

Eye Lens Transperancy and the Role of the Greek Key Super-secondary Structural Motif in the Human ß-? Crystalins
Dorairajan Balasubramanian, Professor, LV Prasad Eye Institute, India

Roles of Interfacial Residues in Conferring Specificity and Stability of Transient Protein-Protein Complexes
Narayanaswamy Srinivasan, Professor, Indian Institute of Science Bangalore, India

Mechanism of Survival of Ethanol Producing Organisms: Role of Cellular Compatible Osmolytes In Counteracting the Deleterious Effects of Ethanol on Structure, Stability and Function of Proteins
Faizan Ahmad, Professor & Director, Jamia Millia Islamia, India

Lipid Transfer Mechanism of Cholesteryl Ester Transfer Protein between HDL and LDL
Sanjib Senapati, Professor, Indian Institute of Technology Madras, India

Arginase of Helicobacter Gastric Pathogens Utilizes a Unique Non-Catalytic Triad for Catalysis; a Possible Strategy to Develop Specific Inhibitors
Apurba Sau, Scientist, National Institute of Immunology, India

FREE

Hindustani Classical Vocal: Prof Subendhu Ghosh,University of Delhi, New Delhi

Punjabi Cultural Program

Conference Dinner

Session 3 Chairperson: D. Balasubramanian

How Does the Prion Protein Misfold?
Jayant Udgaonkar, Professor, National Centre for Biological Sciences, India

Chiral Proofreading: Mechanistic and Functional Implications
Rajan Sankaranarayanan, Staff Research Scientist, Centre for Cellular and Molecular Biology, India

END OF DAY 1

Session 4 Chairperson: Amitabha Chattopadhyay

The Impact of Crystallization Conditions on Structure Based Drug Design: A Case Study of the Brd2 Bromodomain Complex
B Padmanabhan, Professor, National Institute of Mental Health and Neurosciences, India

Structural and Functional Studies of Myosin Ib: Understanding the Role in Phagocytic Cup Formation of Entamoeba Histolytica
Samudrala Gourinath, Associate Professor, Jawaharlal Nehru University, India

Protein Collapse and Folding
Govardhan Reddy, Assistant Professor, Indian Institute of Science, India

Viscoelasticity of Single Proteins and Its Significance in Protein Dynamics
Shivprasad Patil, Assistant Professor, Indian Institute of Science Education and Research, India

Local Modulations in Conformations of Proteins in Presence of Macromolecular Crowding
Pramit Chowdhury, Assistant Professor, Indian Institute of Technology Delhi, India

Tea Break

Session 5 (Young Researcher Talks) Chairperson: R. Sowdhamini

Ratna Phadke Award Talk: Enigmatic World of ß?-Crystallins Beyond the Eye Lens
Shanti Swaroop Srivastava, Senior Research Fellow, Centre for Cellular and Molecular Biology, India

Inhibition of Curli Assembly and Biofilm Formation in E.coli by the Human Systemic Amyloid Precursor Transthyretin
Neha Jain, Postdoctoral Research Fellow, University of Michigan, United States of America

Ion Transfer into the Active Site of DHBPS: Mechanistic Insights from MD Simulations
Ranajit Nivrutti Shinde, Postdoctoral Fellow, Institute of Microbial Technology, India

Computational Approach to Engineer Rationally Designed Nanostructured Molecular Transporters for siRNA Delivery
Sanchita Mukherjee, Post Doctoral Fellow, Indian Institute of Science Education and Research, India

Designed Dominant Negative: A Potent Technology to Study Gene Regulation
Prateek Jain, Doctorate Fellow, National Agri-Food Biotechnology Institute, India

A Tale of Two Paralogs: Human Transformer2 Proteins with Differential RNA-Binding Affinities
Pritha Ghosh, Postdoctoral Fellow, National Centre for Biological Sciences, India

Discussion with Oral Presenters

Lunch Break

Poster Evaluation and Tea

Session 6 Chairperson: M. K. Mathew

Structure and Dynamics of Ternary Bilayers Containing Ganglioside Gm1
Chaitali Mukhopadhyay, Professor, University of Calcutta, India

Studies on p. Falciparum Plasmepsins to Decipher their Functional Mechanism, and Acquire Knowledge for Developing Antimalarial Drugs
Prasenjit Bhaumik, Assistant Professor , Indian Institute of Technology, India

Role of Macromolecular Crowding on Structural, Kinetic and Thermodynamic Properties of Metalloproteins
Rajesh Kumar, Associate Professor, Central University of Punjab, India

Substrate-Induced Dissociation of Competitive Inhibitor: Evidence for Competitive-Allostery
S Kumaran, Principal Scientist, Institute of Microbial Technology, India

Tea Break

Session 7 Chairperson: N. Srinivasan

Insights of Amyloid Interaction Network and Designing Structure based Anti-Amyloidogenic Biomolecules
Bishwajit Kundu, Associate Professor, Indian Institute of Technology, India

Cold Thermal Denaturation in a Globular Protein: Signatures of Early Unfolding Investigated with Computer Simulations
Neelanjana Sengupta, Assistant Professor , IISER , India

Anion Size and Charge modulate Mechanical Stability of Protein: A Single Molecule Force Spectroscopy Study
Deepak Sharma, Senior Scientist, Institute of Microbial Technology, India

3D Structure and Mechanism of Intermediate Filament Assembly
Madhusudhan Mallur Srivatsan, Associate Professor, Indian Institute of Science Education and Research, India

Conference Dinner

Session 8 Chairperson: Jayant Udgaonkar

Inter-Residue Contacts as Critical Targets for Modulating Amyloid Properties
Sudipta Maiti, Professor, Tata Institute of Fundamental Research, India

Notes from the Underground: Role of a Transmembrane Helix in Transmitting Information across a Bilayer
M K Mathew, Professor, National Centre for Biological Sciences, India

END OF DAY 2

Session 9 Chairperson: Sudipta Maiti

Exploring Substrate Promiscuity in Sugar Nucleotidylyltransferases and Identifying Two Commercially Employable Enzymes for Glycorandomisation
Balaji Prakash, Senior Principal Scientist, Central Food Technological Research Institute, India

Evolutionary Classification of Zinc Finger Proteins
Srikrishna Subramanian, Principal Scientist, Institute of Microbial Technology, India

Mechanism and Pharmacology of Neurotransmitter Transport
Aravind Penmatsa, Assistant Professor, Indian Institute of Science, India

Towards Quantitative Descriptions of Biomolecular Dynamics: Molecular Descriptors for Sorting Ubiquitin Family Proteins
Ravindra Venkatramani, Reader, Tata Institute of Fundamental Research, India

RNA Recognition Motifs (RRMs): A Story of one Fold with Different Partners
Neel Sarovar Bhavesh, Staff Research Scientist, International Centre for Genetic Engineering and Biotechnology, India

Tea Break

Session 10 Chairperson: K V R Chary

I Can’t Wait for High Resolution Structures to Discover Lead Compounds”: Story of Isodesmosine
Ashish , Principal Investigator, Institute of Microbial Technology, India

Structural Basis of Ascorbate Recycling
Arockiasamy Arulandu, Staff Research Scientist, International Centre for Genetic Engineering and Biotechnology, India

Chaperone Repertoires and Networks in Archaeal Genomes
Manisha Goel, Assistant Professor, University of Delhi, India

Lunch Break

General Body Meeting

Concluding Session & Awards Proclamation

Tea and Depart