Abstract

From Molecules To Whole Organs

Francesco Pavone, Principal Investigator, LENS, University of Florence

We are interested in the correlations between morphology and functionality, which is one of the major issues in the comprehensions of many pathologies and mechanisms of biology. In the context of the brain, for example, elucidating the neural pathways that underlie brain function is one of the greatest challenges in neuroscience.

Nowadays, there are several imaging techniques offering a complementary approach to visualize intact neural networks. Each of those offers a different strategy and furnish complementary information on the role of neural components.

We will describe different approaches enabling to move from single molecule tracking in neurons, to single cell imaging up to whole brain both on functional and morphological point of view.