Abstract

Point-of-Care Nano Biosensing Technology Based on Big Data

Xianqiang Mi, Professor, Chinese Academy Of Sciences

We are in the era of big data. Digitization of an individual’s ‘-omics’ data like genome, transcriptome, proteome and metabolome information parlays into big data’ informatics which could be used for healthcare. A lot of omics-based biomarkers have been identified. Point-of-care biosensor systems can potentially improve patient care through real-time and remote health monitoring. Our work mainly focus on potentially new technologies in the form of POC biosensors like electrochemical biosensor, fluorescence biosensor etc. We have developed the prototype of intelligent electrochemical microfluid diagnostics system as a potential candidate for point-of-care biosensing applications. In future, requirements such as rapid label-free detection, miniaturized sensor size, portability and wireless networking schemes for a point-of-care environment will be the focus of our work. We hope our nano biosensing system can detect significant omics based biomarkers and provide clinically relevant information in biological samples. , thereby assisting physicians and clinicians for health management. The context of POC approvals by the China FDA will also be discussed.