Abstract

Biomicrofabrication via Low-voltage Electrospinning Patterning

Yan Yan Shery Huang, Lecturer, University of Cambridge

Recent advances in biofabrication technologies offer promising new strategies to create tissue scaffolds and tissue models that could address the pressing need for more sustainable drug screening platforms, and personalised tissue and organ part replacements. The creation of a support matrix that recapitulates the bioactive and structural roles of the extracellular matrix (ECM) may hold the key in making functional, complex tissues. However, cross-length scale biochemical and structural biomimicry is unattainable with a singular fabrication technique. Our recent development in Low-voltage Electrospinning Patterning (LEP), and its integration with additive manufacturing, opens up new avenues in the creation of geometrically defined biomaterial matrices.