Abstract

Creation of Functional Tissue with a Novel 3D Printing Technology

Shizuka Akieda, Chief Executive Officer, Cyfuse Biomedical K.K.

Cyfuse is a regenerative medicine start-up focused on creation of functional 3D tissues and organs. The proprietary “Kenzan method” skewers multiple cellular aggregates with fine needles until cells fuse entirely in a few days. Our Bio 3D Printer, “Regenova” automated this skewering process and is designed to help researchers try various cell populations and culture conditions to discover a protocol of manufacturing functional organs. The system was launched commercially in Japan and US. The examples of cellular products include Blood Vessels, Peripheral Nerve Regeneration, and functional liver for drug discovery. Further applications with neural cells and cardiomyocytes are currently being explored by Japanese and US academia.