Abstract

Multiple Biomarker Analysis: New Approaches and Workflow Solutions

Martin Schlumpberger, Associate Director, QIAGEN

Isolation of circulating cell-free biomarkers from different types of body fluids and different entities within these samples, such as circulating tumor cells (CTC) or exosomes and other extracellular vesicles (EVs), poses diverse challenges that need to be addressed. QIAGEN recently released new solutions that include exoRNeasy protocols for isolation of short and long RNAs from EVs in urine, or isolation of cell-free miRNA in higher throughput. Our data demonstrate that utilizing different technology approaches in combined workflows allows collection of meaningful biological data at unprecedented depth, enabling new insights into pathological processes that have a direct impact on clinical research parameters, such as survival statistics.

The applications presented are for molecular biology use only. Not for use in diagnostic procedures.