Abstract

Image-based Measurement Systems and Image-Processing Tools for Micromixers and Droplet Microfluidics

Gökhan Ergin, Product Manager, CTA & Microfluidics, Dantec Dynamics A/S

Image-based sensor systems are quite popular in micro-scale flow investigations due to their flexibility and scalability. In particular, PIV systems and related image processing tools can be used in a myriad of applications, including (but not limited to): Mixing of chemicals, droplet formation, drug delivery, cell counting, cell sorting, cell locomotion, object detection, and object tracking. The intention is to provide some application examples to demonstrate the use of image processing solutions to overcome certain challenges encountered in microfluidics. These solutions are often in the form of image pre- and post-processing techniques, and how to use these will be described briefly in order to extract the relevant information from the raw images. In particular, two main application areas are covered: Micro mixing, and droplet formation. For each application, a flow field investigation is performed using Micro-Particle Image Velocimetry (µPIV). Both two-component (2C) and three-component (3C) µPIV systems are used to generate the reported results, and a brief description of these systems are included. The results include detailed velocity, concentration and interface measurements for micromixers, and phase-separated velocity measurements for the micro-droplet generator.