Abstract

Multiparameter Phenotyping and Characterization of EVs - Direct from Complex Biofluids With No Purification

Ben Owen, Regional Sales Director, NanoView Biosciences, Inc.

When studying EVs in a diagnostic capacity, understanding the nature and role of EV sub-populations is of paramount importance. Existing technologies either struggle to measure EVs due to their small size and/or are unable to link proteomic information to physical characterization at the single EV level. NanoView provides a multiparameter measurement of single EVs at the smallest sizes. The technology is able link proteomic information of surface and luminal proteins to physical characterization, without the need for any sample purification. Up to 4 surface and luminal proteins can be colocalized on single EVs