Abstract

On-chip Surface Acoustic Wave and Micropipette Aspiration Techniques to Assess Cell Elastic Properties

Yanqi Wu, PhD candidate, The University of Melbourne

Cells in vivo mechanically interact with the local microenvironment, stressing the important role of cell mechanical properties in cellular behaviours. We built a phase-modulated surface acoustic wave microfluidic device measuring cellular compressibility (or bulk modulus) and a microfluidic micropipette-aspiration device measuring cellular Young’s modulus, facilitating the investigations of cellular elastic properties and cytoskeletal mechanics.