Abstract

Magnetic 3D Cell Culture as an Enabling Tool

Glauco Souza, Director of Global Business Development and Innovation, 3D Cell Culture, Greiner Bio-One

The growing push for 3D cell culture models is limited by technical challenges in handling, processing, and scalability to high-throughput applications. To meet these challenges, we use our platform, magnetic 3D cell culture (M3D), in which cells are individually magnetized and assembled with magnetic forces. In magnetizing cells, not only do we make routine cell culture and experiments feasible and scalable, but we also gain control in the formation and manipulation of spheroids and more complex structures. This presentation will focus on recent developments using this platform. Specifically, we will present a tool for manipulating cells and phenotypic profiling of cell types within spheroids. Overall, we apply M3D to improve the development of in vitro microphysiological systems and applications.