Abstract

Using Neuronal Enriched Extracellular Vesicles To Determine Brain Health

Lynn Pulliam, Professor of Laboratory Medicine and Medicine, University of California-San Francisco

Circulating plasma EVs can be captured by a neuronal surface protein (L1CAM) and the cargo interrogated to determine the health of neurons in real time. We have used protein arrays to look at neuronal EV cargo in people with HIV or post-COVID cognitive impairment.