Abstract

Immunological Senescence Impacts Tissue Stem Cells and Wound Healing in Space

Sonja Schrepfer, Professor of Surgery, University of California-San Francisco

Spaceflight causes a suite of negative health effects that may be comparable to immuno-senescence, which seems to be a key regulator of the regenerative capacity of tissue- and organ-specific stem cells. Our data aim to understand the role of immuno-senescence on the regenerative capacity of tissue-specific stem cells.