Abstract

Towards a Functional Micro-Organ Model of Human Cardiovascular Stiffness-related Diseases in Microgravity and on Earth

David Sachs, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai

We are developing a functional micro-organ model of the human cardiovascular system, containing iPSC-derived cardiac and vascular components linked in a circulatory system. In partnership with Space Tango, we will use this system on the ISS to model cardiovascular stiffness related diseases in microgravity.