Abstract

Microfluidic Deformability Cytometer Applied to Pathology Analysis

Magalie Faivre, , University Of Lyon

A microfluidic device consisting of an oscillating width channel was used to obtain the mechanical signature of red blood cells. We have demonstrated that by monitoring the shape and dynamics of cells exiting the last geometric restriction, we have managed to discriminate between blood samples from healthy donnors and patients with malaria, sickle cell disease and hereditary spherositosis.