Abstract

PKU-SMART-Sensor: An Integrated Point-of-Care System for the Self-Testing of Phenylalanine in Biological Specimen

Salvatore Petralia, Assistant professor, University of catania

PKU-SMART-Sensor is an an integrated Point-of-Care system composed by a miniaturized and low-cost biosensor, a reader for thermal processes and optical reading, wirelessly connected with a smartphone for the remote control and data acquisition. The biosensor integrates all the processes required for the Phe monitoring as: [1] sample treatments, [2] enzymatic recognition based on Phenylalaninedehydrogenase/NAD+-dependent and [3] colorimetric-transduction process based on the in-situ formation of plasmonic gold nanostructures.