Abstract

Opportunities for Iodine Reagents in Flow Synthesis

Thomas Wirth, Professor, Cardiff University

The development of catalytic reactions based on stoichiometric reactions using iodine-based reagents will be discussed. Novel chiral reagents and catalysts allow the easy synthesis of versatile scaffolds as synthetic building blocks as well as applications towards total synthesis. The direct electron transfer at electrode surfaces is one of the prototypical green technologies of the future and the use of microreactors further advances and simplifies that technology. The use of a robust and flexible flow microreactor for electrochemistry will be presented for the facile generation of iodine(III) reagents. Examples of stereoselective iodine(III)-mediated electrochemical reactions are being discussed.