Abstract

A Novel Microfluidic Platform for Biomedical Applications –Thin-film Direct Coating (TDC) Technology

An-Bang Wang, Distinguished Professor, Institute of Applied Mechanics, National Taiwan University

Microfluidics can bring significant advantages in various applications, e.g., chemical reaction, process control and bio-medical detection etc. In the past twenty-five years, we shifted the research topics from different microfluidic components, including micropump, microvalve, and micromixer etc., to various integration systems for industrial applications, e.g., microreactor / multi-emulsion generators, high-throughput fluid / flow properties analyzer, and the maskless pattern coating system by multi-phase microfluidic technology, etc. Special efforts were made for microfluidic applications in the life science studies and clinical diagnoses with the advantages of fast, easy use, and excellent cost performance, e.g., a sequential lab-on-a-chip control for biomedical point-of-care testing. Recently, an extremely material- and time-saving TDC (Thin-film Direct Coating) microfluidic platform for fast immunoassay and detection, e.g., the fast TDC WB (western blotting) strip for fast evaluation of neutralizing response to SARS-CoV-2 and fast TDC IHC (Immunohistochemistry) was developed and tested for the future practical use.