Abstract

Immiscible Aqueous Droplets for Biosensing, Wound Healing Models, and Exosome Manipulation

Shuichi Takayama, Professor, Georgia Research Alliance Eminent Scholar, and Price Gilbert, Jr. Chair in Regenerative Engineering and Medicine, Georgia Institute of Technology & Emory University School of Medicine

Liquid-liquid phase separation (LLPS) occurs physiologically inside each of our cells. LLPS can also be observed with various polymer systems such as poly(ethylene glycol) PEG, dextran (DEX) where immiscible aqueous two-phase systems (ATPS) are formed. This talk will describe ATPS fundamentals as well as application of ATPSs in cellular biopatterning including for wound healing studies, exosome isolation, and molecular biosensing.