Abstract

Developing New Microflow Processes Using Classical Reagents

Shinichiro Fuse, Professor, Nagoya University

Classical electrophiles such as thionyl chloride, phosphorus trichloride, phosphorus tribromide, and triphosgene are useful because they are inexpensive, readily available, less wasteful, and highly active. However, their high electrophilicity often causes undesired reactions. Microflow technology allows precise control of both short reaction time and temperature. Therefore, the combination of microflow technology and classical electrophiles opens the door to developing new useful chemical processes. In this talk, I will introduce our developed microflow synthetic processes that cannot be achieved under conventional batch conditions.