Abstract

Has the Flow Changed? From Microfluidic Research to Meso Reactor Synthesis

Paul Watts, Distinguished Professor and Research Chair, Nelson Mandela University

When microfluidic reactor technology was first introduced it was seen as being a research and development tool suitable for small scale production, however it is now being used to produce large quantities of product. The key driver in these examples being safety, where the excellent mixing and heat transfer characteristics of micro structured reactors enables these highly exothermic reactions to be safely performed. Nevertheless there is now a plethora of commercial reactors on the market, which means that most companies are investigating this technology to rapidly screen reactions utilising continuous flow, leading to the identification of reaction conditions that are suitable for use at a production level. It is this system flexibility that has the potential to reduce both the time taken and risk associated with transferring reaction methodology from research to production. A selection of reactions demonstrated using this technology will be outlined, which enable local production within Africa.