Abstract

High-Throughput Multimodal Label-Free Cell Separations

Ian Papautsky, Professor, University of Cincinnati

Inertial microfluidics shows tremendous potential for high-throughput cell separations in biomedicine. The approach relies on hydrodynamic forces to manipulate cells in microfluidic channels for size-based focusing and ordering. This presentation will summarize our recent work in this emerging field. Simple inertial microfluidic systems that offer complete separation of cells at high throughput will be discussed, with emphasis on efficiency, cell purity, and yield. Novel and advanced multi-stage inertial migration devices and their applications to cell sorting and counting will be described.