Abstract

3D Microtumor-based Combinatorial Drug Discovery

Jens Kelm, CEO and Co-Founder, PreComb Therapeutics AG

3D tissue culture technologies for drug discovery are becoming of age. However, new 3D technologies and models are primarily used to exchange existing models to improve individual aspects in the developmental process. However, 3D models do not only reflect tissue and organ disease biology better than 2D models they allow to create novel assays to build completely new drug development processes. To take full advantage of 3D we present a 3D-based discovery processes to develop novel drug combinations.