Abstract

Tissue Manufacturing by Bioprinting: Challenges and Opportunities

Fabien Guillemot, Chief Executive Officer, Poietis

Despite substantial investments to meet clinical and commercial expectations, and while scientific achievements at the preclinical research stage have sometimes been impressive, scaffold-based Tissue Engineering approaches are struggling to find the way to therapeutic and industrial success. Main challenges for the manufacturing of tissue engineered ATMPs concern the improvement of the standardisation of manufacturing processes, tissue functionality, and cost-effectiveness and profitability of related treatments.
 
Based on our experience in the field of bioprinting, we discuss how this technology – thanks to its characteristics resulting from the convergence of automation, biology and digital technology – should make it possible to overcome current tissue manufacturing bottlenecks and also provide new opportunities.