Abstract

Electrochemical Analysis of Vasculature-on-a-Chip and Vascularized-3D-Model-on-a-Chip

Yuji Nashimoto, Associate Professor, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University

During this decade, bioengineering technologies to make a perfusable vascular model and integrate it with a three-dimensional culture model shows great advancement. However, analytical systems to evaluate vascular function and its effects are still limited. In this presentation, the electrochemical platform to evaluate vascular permeability, topography, and the transvascular flow effects on 3D tissue will be demonstrated. The analytical platform is promising for read-outs of the functionality of the vascular model and vascularized 3D model in a microphysiological system.