Abstract

Integrated Methodology For Extracellular Vesicle Purification, Characterization and Linking Biophysical Properties to Biological Function

Anoop Pal, Chief Operating Officer-Americas, iZON Science Ltd.

Extracellular Vesicles (EVs) are heterogeneous in size, number, membrane composition and contents. A thorough understanding of this diversity and the linkage of biophysical properties to EV biological role and function is necessary. Real, validated, repeatable measurement data are required for the biomedical adoption of EV based diagnostics and therapeutic developments. These have not always been prominent in EV research. Izon Science has developed an integrated, standardizable and very practical methodology for EV purification and biophysical characterization amenable for diagnostic and therapeutic proposes.