Abundant, Ultra-Short Trans-Renal Tumor DNA Fragments in Urine For Non-Invasive Cancer Detection and Monitoring
Qing Kang, Senior Scientist, Syros Pharmaceuticals, Inc.
Circulating tumor DNA (ctDNA) has shown great promise as a cancer biomarker in detecting tumor genotypes, monitoring cancer recurrence and resistance, as well as assessing treatment response. Compared to increased studies in plasma ctDNA, trans-renal tumor DNA (trDNA) exists as a largely untapped field. Here we present a proof-of-concept study to comprehensively understand the fundamentals of trDNA in different cohorts of cancer patients.
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