Abstract

Identifying and Validating Cellular Targets of Cancer using Somatic Stem Cells

Prithi Rajan, Adjunct Faculty- Chemical Physiology, The Scripps Research Institute

This talk will discuss a couple of ideas where novel targets related to cancer, specifically gliomas, are studied using somatic stem cells along with other primary cultures.   Neural and mesenchymal stem cells are used as experimental paradigms to explore alternative activation of the Stat signalling pathway, and potential interactions between cells within the tumor vis-à-vis immune reactions.  The use of stem cell technology to study the cancer and stem cell states will also be discussed.