Abstract

Reveal the Nanoworld with NanoSight Pro

Agnieszka Siupa, Product Manager, Malvern Panalytical

Developing therapeutics using invisible drug delivery systems brings many challenges in biophysical characterization. During process and formulation development, there is a need to monitor sample purity and stability at many points to help guide the next step. Garnering detailed information of these complex systems to fully correlate their composition to their therapeutic effect is also crucial. NanoSight Nanoparticle Tracking Analysis (NTA) has become a standard toolbox in the characterization of biomaterials including extracellular vesicles, drug delivery systems, viral vectors and protein aggregates. NTA provides visual confirmation and high-resolution size and concentration data in minutes allowing the instant assessment of sample stability, but also complexity. With the introduction of the new NanoSight Pro, characterization becomes even easier, quicker and more accurate than before. Packed with smart features, the NanoSight Pro provides greater sensitivity in biologics detection, high reproducibility and enhanced fluorescence measurements for detecting sample subpopulations. Powered by machine learning algorithms, measurement subjectivity is reduced and automated processing enabled to assure superior Nanoparticle Tracking Analysis.