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SELECTBIO Conferences Flow Chemistry Asia 2019

Abstract



Towards Automation: Continuous-Flow Synthesis of APIs

Wu Jie, Assistant Professor, Chemistry Department, National University of Singapore

Compared to stepwise batch synthesis, multistep continuous flow synthesis enables the combination of multiple synthetic steps into a single and uninterrupted reactor network, thereby circumventing the need to isolate intermediates, and enabling automated synthesis. However, despite many advantages and much progress in end-to-end API continuous-flow synthesis, several hurdles still need to be overcome. For instance, solvent and reagent incompatibility between individual steps, build-up pressure of reactors, substrate dispersion, and requirement of regeneration of reagent and scavenger columns. I this talk, I will present our recent progresses in this research field, which enables a novel automated API synthesis platform.


Add to Calendar ▼2019-11-14 00:00:002019-11-15 00:00:00Europe/LondonFlow Chemistry Asia 2019Flow Chemistry Asia 2019 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com