Abstract

Determinants of Antibody Immunotherapy

Mark Cragg, Professor and Chair in Experimental Cancer Biology, Centre for Cancer Immunology, University of Southampton, Southampton General Hospital

There is growing appreciation of the depth of interaction between tumour cells and their surrounding microenvironment. These interactions augment tumour growth, proliferation and mediate immune suppression. Of critical importance is how these interactions affect antibody immunotherapy and how they might be targeted to improve treatment efficacy. This presentation will discuss several key determinants of antibody immunotherapy.