Abstract

Lab on a Chip Devices for Chemical Analyses on Cell Phones

Daniel Filippini, Professor, Linkoping University

Cell phones are the most ubiquitous consumer electronic devices and constitute a widespread infrastructure attractive for distributed chemical sensing. However, despite of integrating varied and sophisticated physical sensors, to incorporate equivalent chemical-sensing capabilities has been elusive. Current instrumentation approaches for chemical sensing using cell phones, which couple to peripherals that are scarcer than the phones, tend to limit the ubiquity of these solutions. To preserve the cell phone ubiquity, disposable lab-on-a-chip devices, which are conceived as only accessory for chemical detection, offer an attractive alternative. In this work such devices and the employed fabrication methods are considered. Thus, stereo lithography 3D printing techniques for low-cost fast prototyping of microfluidics and optics are discussed, as well as the detection principles best suited to the phones’ resources. In this case angle resolved surface plasmon resonance detection of b2 microglobulin and autonomous lab-on-a-chip devices for quantitative glucose and glutamate detection are presented.