Abstract

Optofluidic Systems For On-Chip Molecular Diagnostics

Holger Schmidt, Narinder Kapany Professor of Electrical Engineering, University of California-Santa Cruz

Optofluidic devices have emerged as the basis for ultra-sensitive, amplification-free analysis of single molecules. We will describe the core features and capabilities of this approach and discuss recent advances in the areas of integration of multiple functions on a single chip, optical detection and analysis with maximized efficiency, and representative examples such as multiplex detection of single antibiotic resistant bacteria and SARS-CoV-2 detection.