Abstract

Putting 3D Bioprinting to the Use of Tissue Model Fabrication

Y. Shrike Zhang, Assistant Professor of Medicine and Associate Bioengineer, Harvard Medical School

The talk will discuss our recent efforts on developing a series of bioprinting strategies including sacrificial bioprinting, microfluidic bioprinting, and multi-material bioprinting, along with various cytocompatible bioink formulations, for the fabrication of biomimetic in vitro 3D tissue models to achieve improved drug screening and biological studies. These platform technologies, when combined with microfluidic bioreactors and bioanalysis, will likely provide new opportunities in constructing functional microtissues with a potential of achieving precision therapy by overcoming certain limitations associated with conventional models based on planar cell cultures and animals.