Abstract

Microfluidic Cellular Engineering System For Precision Immunotherapy

Mei He, Assistant Professor, University of Kansas, Chief Science Officer of Clara Biotech

Cells as the smallest units of the material body are taking tremendous roles in maintaining human body functions. Modifying cells as the factory to produce essential biomolecules are of substantial economic and scientific interest. In addition to the production of proteins, metabolites, and enzymes, engineering and production of exosomes are emerging for developing precision immunotherapy agents and personalized medicine. We will report novel microfluidic approaches for manipulating cellular functions in producing tailored extracellular vesicles and exosomes for advancing the cancer immunotherapy.