Abstract

Quantitative Pharmaceutical Analysis using Transmission Raman Spectroscopy

Abid Zainul, Product Specialist- Molecular Spectroscopy, Agilent Technologies India Pvt Ltd.

Transmission Raman spectroscopy technique can be used for QC analysis of oral solid dosage (OSD) samples, powders, and more. The presentation will discuss how this technique can reduce content uniformity (CU), assay, and ID of intact tablets and capsules to 10 seconds or less. This helps laboratories eliminate sample preparation, consumables, solvents, and highly skilled technicians that are required in other techniques. The ability to quantify different polymorphs and solid-state forms makes the this system a quick and sensitive adjunct to X-ray diffraction techniques.