Single Molecule Screening
Joshua Edel, Professor, Imperial College London
Analytical Sensors play a crucial role in today’s highly demanding
exploration and development of new detection strategies. Whether it be
medicine, biochemistry, bioengineering, or analytical chemistry the
goals are essentially the same: 1) improve sensitivity, 2) maximize
throughput, 3) and reduce the instrumental footprint. In order to
address these key challenges, the analytical community has borrowed
technologies and design philosophies which has been used by the
semiconductor industry over the past 20 years. By doing so, key
technological advances have been made which include the miniaturization
of sensors and signal processing components which allows for the
efficient detection of nanoscale object. One can imagine that by
decreasing the dimensions of a sensor to a scale similar to that of a
nanoscale object, the ultimate in sensitivity can potentially be
achieved - the detection of single molecules.
|
|