Abstract

Optical Molecular Sensing and Imaging of Cancer

Mark Bradley, Professor of Therapeutic Innovation, Precision Healthcare University Research Institute, Queen Mary University of London

In my talk I will describe a number of technologies that have come out of the Proteus project that has, as its focus, the use of light (of a variety of flavors) to sense and image disease. This includes:
(i). The use of optical fibers for measuring pH around tumors;
(ii). The application of chemical probes that can paint disease (bacterial infection and cancer will be illustrated);
(iii). The use of novel CMOS SPAD detectors that allows for rapid full spectral fluorescent lifetime imaging to be used in the analysis of cancerous tissues (targeting cancer margin detection).