Abstract

The Celsee™ PREP Platforms: Simplified Rare Single Cell Capture and Isolation

Kalyan Handique, CEO & President, Celsee Diagnostics

The ability to capture rare cells of interest from heterogeneous cell suspensions or blood and to individually characterize them has, historically, been technically challenging with a significant time and financial commitment. In this presentation, Celsee Diagnostics will discuss the Celsee PREP100 and the Celsee PREP SingleCell platforms that use streamlined, simplified microfluidic technologies to detect, enrich, and characterize rare cell populations and individual cells. The starting specimen is passed over a microfluidic chip containing tens of thousands to hundreds of thousands of individual capture wells. Cell size and morphology define which cells are captured – no fluorescent probes are needed. Three optional analysis paths exist for captured cells: on-chip immunochemistry, DNA or mRNA FISH assays, the cells retrieved for off-chip characterization including PCR, NGS and culture, or individual single cells can be isolated and retrieved.