Abstract

Graphene-based Printed Biological and Chemical Sensors for Point-of-Care Diagnostics

Adisorn Tuantranont, Director, Thai Organic and Printed Electronics Innovation Center (TOPIC), National Electronic and Computer Technology Center (NECTEC), National Science and Technology Development Agency (NSTDA)

In this invited talk, we will present our recent research on graphene, which covers synthesis, fabrication, characterization and applications of graphene-based biological and chemical sensors for point-of-care diagnostics. Graphene is synthesized by electrolytic exfoliation method and used to produce graphene-PEDOT:PSS conductive ink that has been applied for various electrochemical sensing applications. Firstly, we reported inkjet-printed graphene-PEDOT:PSS modified screen printed carbon electrode (SPCE) for electrochemical detections of three common electroactive analytes, including hydrogen peroxide (H2O2), nicotinamide adenine dinucleotide (NAD+/NADH) and ferri/ferro cyanide (Fe(CN)63/4) [1]. In addition, graphene-PEDOT:PSS modified SPCE demonstrated highly sensitivity and selectivity for detections of glucose, salbutamol and glutathione [2-4]. Furthermore, graphene prepared by electrolytic exfoliation is combined with copper phthalocyanine-polyaniline and employed to a modified SPCE for selective electrochemical sensing of ascorbic acid [5]. Moreover, graphene-carbon paste composite electrode has been fabricated and applied as disposable electrochemical sensors [6]. The graphene-carbon paste material is also studied for biocompatibility with cancer cells to evaluate the possibility of cell-based bio-sensing applications [7].