Abstract

Lab on Discs for Diagnostics and Process Control

Anja Boisen, Professor, Technical University of Denmark

The optics and mechanics from a DVD player can be used to realize compact and sensitive sensor systems. By rotating a disc with integrated microfluidic channels it is possible to manipulate liquid samples such as blood – performing crucial operations like separation, valving and mixing. We integrate cantilever-based sensors, electrochemistry, surface enhanced Raman spectroscopy (SERS), nanoparticles and resonating strings with centrifugal microfluidics. The sensors are read out by a DVD pick-up head which can perform transmission, absorption measurements and which can detect nm deflections. Also, electrodes are integrated on a disc platform, facilitating the electrochemical measurements. Applications within diagnostics and process monitoring will be highlighted.