Abstract

Organ-on-a-Chip: A Paradigm Shift for Drug Development and Personalized Medicine

Holger Becker, Chief Scientific Officer, microfluidic ChipShop GmbH

This section of the course will offer a broad introduction into the organ-on-a-chip field for scientists, technicians, engineers but also business developers who would like to develop a deeper understanding of this technology for the use in drug development and personalized medicine. The course covers basic principles of organ-on-a-chip (OoaC) or microphysiological systems (MPS), discusses material and manufacturing aspects of such devices and provides an overview over current solutions both for single organ and multi-organ systems. Insights into the development of the OoaC market and commercialization strategies will be given, together with application examples in different fields.

Learning Objectives

• Understand the basic concept of organ-on-a-chip technology
• Learn about different materials and manufacturing methods available for the realization of OoaC devices.
• Understand economic aspects in the development and manufacturing of OoaC devices and systems.
• Learn about examples of currently available OoaC devices and their commercial applications.
• Understand the current state of the markets and obstacles in the commercialization process.

• Motivation for OoaC technology
• Physical and biological principles of the technology
• Materials and manufacturing methods for OoaC devices
• Examples for applications and products
• Aspects in commercializing OoaC devices and systems
• Conclusions