Assay Miniaturization Strategies: Smaller and Cheaper Cell-Based Assays for HCA
Anthony Davies, Director, Trinity College Dublin
To sustain the viability of
large-scale research programs running in academia and industry (especially when
considering the current global economic climate), it is essential to reduce
research costs wherever possible. With the advent of micron resolution
robotics and nano-litre capable liquid handlers, assay miniaturization for
large-scale High-Content Screening is now possible. The advantages of
miniaturization are clear, when one considers the savings in reagents and
experimental materials and experimental turnaround times. However
miniaturization can also be costly to set up and difficult to deploy.
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