Abstract

Extracellular Vesicles in Cytokine Regulation

Leonid Margolis, Head, Section of Intercellular Interactions, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, NIH

Extracellular vesicles play an important role in human immuno-modulation mediated by cytokines both in normal condition and in pathologies. We found that both myocardial infarction and in HIV-1 infection extracellular vesicles are associated with immune activation, an important driver of the disease.