Abstract

Circulating Tumor Cells to Guide Treatment of Cancer Patients

Leon Terstappen, Chair Medical CellBiophysics, MIRA Research Institute for Biomedical Technology and Technical Medicine, University of Twente

The presence of Circulating Tumor Cells (CTCs) enumerated with the CellSearch system is associated with relatively poor survival and their reduction after the first weeks of therapy indicates a response to therapy.  Present research focus is on the ability to extract treatment relevant information from the proteins, RNA and DNA in these CTC.