Abstract

Organ Printing as an Information Technology: Towards Tissue and Organ Informatics

Rodrigo Rezende, Post-Doc Researcher, Center for Information Technology Renato Archer

Organ printing is a computer-aided robotic additive biofabrication of human organs. 3D bioprinting is now considered as an emerging information technology and the effective application of existing information technology tools and development of new technological platforms are essential for progress in organ printing. The information technology and computer-aided design software are instrumental in the transformation of virtual 3D bioimaging information about human tissue and organs into living biological reality during 3D bioprinting. Information technology enables designing blueprints for bioprinting of human organs as well as predictive mathematical modeling and computer simulation both bioprinting and post-printing processes. The design of intraorgan vascular tree, computer simulations of postprinted tissue spheroids fusion and development of virtual organ biofabrication line have been developed. Virtual manufacturing or, more specifically, virtual organ biofabrication line is an information technology based approach for effective design, simulation and optimization of future organ bioprinting plant as an integrated biofabrication process. Thus, the application existing and development of new information technologies such as scaffold, tissue and organ informatics is an important technological imperative for advancing organ bioprinting technology. Moreover, it is safe to predict that with progress and advancing in organ printing technology the software will increasingly dominate the hardware.