Abstract

Three-Dimensional Approach to Study Cancer Immunotherapy

Haruka Yoshie, Application Specialist, CELLINK

Cancer is known for its complexity and due to its complexity, treatment is difficult. A significant effort and progress have been made in cancer therapy, including cancer immunotherapy. To better understand the disease, it is important for the tumor microenvironment to be closely recapitulated in studying cancer models. There has been an increasing number of 3D cell culture studies recently as it represents the native environment of our body more accurately. There are several approaches to study 3D models including organoids and organ-on-a-chip. Here we present the 3D bioprinting technology and its recent applications in cancer immunotherapy. Furthermore, bioprinting applications in other cancer studies including drug screening and tumor-on-a-chip will be discussed.