Abstract

Magnetic Ranking Cytometry: A New Tool for Liquid Biopsy and Subtyping of Rare Cells

Shana Kelley, Principal Investigator, University Of Toronto

The heterogeneity and diverse phenotypes circulating tumor cells makes the analysis of these markers for liquid biopsy a challenge.  We have developed a new technique, magnetic ranking cytometry, that is able to separate CTCs based on phenotypic and genotypic properties.  In a single measurement, CTCs can be separated and classified according to protein expression, gene expression, or functional properties like chemotaxis.